PhD in Biomolecules: Structure-Function-Dynamics

University of Göttingen

Program Description

PhD in Biomolecules: Structure-Function-Dynamics

University of Göttingen

PhD in Biomolecules: Structure-Function-Dynamics


Degree: Promotion/Ph.D. (Dr.rer.nat)/ (Ph.D.)
Standard period of study: 6 semesters
Starting semester: Summer and winter semester
Application: limited admission (application to faculty)
Language skills: Englisch (proof required)

The doctoral program "Biomolecules: Structure – Function -Dynamics" is a member of the Göttingen Graduate School for Neurosciences and Molecular Biosciences (GGNB). It is hosted by the Göttingen Center for Molecular Biosciences (GZMB) and is conducted jointly by the University of Göttingen, the Max Planck Institute for Biophysical Chemistry, the Max Planck Institute for Experimental Medicine, and the German Primate Center.

The research-oriented program is taught in English and open to students who hold a Master's degree (or equivalent) in the biosciences, chemistry, physics, medicine, or related fields.

The Biomolecules program provides training for doctoral students with a special interest in understanding cellular functions at the molecular level. Students should become experts in studying the structure and function of biomolecules at an atomic or molecular level, and they will also be trained in biophysical chemistry and cell biology in order to understand molecular function in a cellular context.

Research


Research focuses on the structure, function and dynamics of biological macromolecules and macromolecular assemblies, with particular emphasis on cellular function of proteins, membranes, protein-nucleic acid complexes. Research projects deal with chromatin remodelling, vesicular transport, membrane fusion, nucleocytoplasmic transport and the nuclear pore complex, the spliceosome and other ribonucleoprotein complexes, and regulatory networks in microorganisms. All these projects share common goals including biochemical reconstitution, as well as biophysical and structural understanding of the processes involved.

In recent years, Göttingen has developed into one of the leading centers of structural biology. Currently there are four groups applying NMR-spectroscopy, five groups using X-ray crystallography, and one applying single-particle cryo-electron microscopy. These approaches are complemented by biophysical methods (fluorescence- and CD spectroscopy, calorimetry, EPR-spectroscopy etc). The analysis of three-dimensional structures also includes theoretical approaches on the structural dynamics of biological macromolecules. Many of these groups are united in an already well advanced initiative for a new DFG Collaborative Reseach Center. Furthermore, the program closely cooperates with the thematically related DFG Research Training Group "Protein-protein interaction during intracellular transport of macromolecules (GRK 521), and it is planned to apply for a new DFG Research Training Group that is thematically centered in this program.

Study


The doctoral program "Biomolecules: Structure - Function - Dynamics" is a member of the Göttingen Graduate School for Neurosciences and Molecular Biosciences (GGNB). The graduate school offers a joint modular training program to which the twelve doctoral programs of GGNB contribute and that is open to all GGNB students. In addition to a lecture and seminar program, training consists of (1) individual counselling by thesis committees, (2) intensive methods courses of 1-3 weeks in special training labs, (3) 2-3-day methods courses in the laboratories of the participating faculty, (4) professional skills courses such as scientific writing, presentation skills, intercultural communication, project management, team-leadership skills, conflict resolution, ethics, and career development, and (5) student-organized scientific meetings, industry excursions, and intercultural events. Students are able to tailor their individual curriculum by choosing from a large number of courses and events.

The Biomolecules program provides training for doctoral students with a special interest in understanding cellular functions at the molecular level. Students should become experts in studying the structure and function of biomolecules at an atomic or molecular level, and they will also be trained in biophysical chemistry and cell biology in order to understand molecular function in a cellular context.

The program contributes to GGNB training with seminars on biochemistry, microbiology and structural biology, short methods courses in state-of-the-art techniques for the quantitative analysis of protein-protein interactions, enzyme kinetics, and bioinformatics, both at an introductory and advanced level. Furthermore, the program is responsible for new Bioanalytics lab facilities (established in 2008) and the associated extended methods course.

Experimental research constitutes the major component of the doctoral studies and is conducted in the laboratory of a faculty member of the doctoral program. Doctoral research projects are complemented by a school-wide training program, offered to all GGNB students, who are members of a vibrant international research community. The language of the doctoral program is English.



Last updated May 23, 2016
Duration & Price
This course is Campus based
Start Date
Start date
Oct. 2016
Duration
Duration
6 semesters
Full time
Price
Price
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Deadline
Start date Oct. 2016
Place
Germany Göttingen, Lower Saxony
Application deadline Request Info
End date Request Info
Duration 6 semesters
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