Lines of investigation
These are the lines of research of this doctoral program:
Cellular and circuital bases of epilepsy. Control of excitability and modifications of synaptic plasticity
Cellular and molecular basis of basal ganglia physiology. Modifications of synaptic plasticity in extrapyramidal pathologies such as Parkinson's disease, Huntington's, dyskinesias, etc.
Cellular and molecular bases of memory and learning. Phenomena of synaptic plasticity and its modifications in dementias (Alzheimer's disease), etc.
Cellular and subcellular bases of the function of potassium channels and receptors for neurotransmitters in the auditory system
Molecular and cellular bases of neuronal plasticity. Molecular and cellular mechanisms related to long-term neuronal plasticity.
Subcellular bases mediating the association and functional coupling between receptors for neurotransmitters and ion channels in the central nervous system
Biomarkers of Stroke.
Development of artificial implants for regeneration of peripheral nerves
Early detection of Alzheimer's disease based on the combination of different markers
Dissection and search for new pharmacological targets. Study of the mechanisms of action of possible new neuroprotective drugs. Participation of mitochondria and second messengers in neurodegenerative processes.
Parkinson's disease and other parkinsonisms / Dementias / Prion diseases / Dysautonomia Drug-resistant epilepsies
Study of the innervation of the axonal segment of the main neurons of the cerebral cortex
Study of the mechanisms of action of possible new neuroprotective drugs
Study of the mechanisms that guide the visual attention and of the corticotalámicas interactions
Expression of factors that prevent postlesional regeneration of nerve connections by the application of small inhibitory molecules such as siRNAs and antagomirs.
Physiology of synaptic transmission.
Genesis and control of motor orders with special emphasis on extraocular and facial motor systems.
Genetics of multiple sclerosis.
Cellular and subcellular localization of ion channels in the central nervous system.
Cellular and subcellular localization of ion channels in the CNS and its functional implications: role of potassium channels in the normal and pathological CNS function.
Cellular and subcellular localization of receptors for neurotransmitters in the central nervous system.
Magnetoresception in "Drosophila melanogaster": physiology of the detection of magnetic fields and the effects that these fields can have on living organisms.
Mechanics of cochlear, cochlear nuclei, cochlear implants
Cellular and molecular mechanisms of adaptation of central auditory neurons to acoustic trauma.
Cellular and molecular mechanisms of degeneration, adaptation and repair / regeneration in deprived neurons of synaptic inputs in models of deafness.
Brain mechanisms underlying memory processes and their deterioration.
Neurophysiological mechanisms involved in the sleep - wake cycle and visual processing
Microglial phagocytosis in the adult hippocampus in health and disease
Cerebral microvascularization: study of its structure and function, the mechanisms involved in its maintenance, regulation, development and plasticity in physiological and pathological conditions
Neural stem cells and neurogenesis in aging and epilepsy
Hearing Neurobiology and Hearing Disorders
Cellular Neurobiology Synaptic genesis, mechanisms of regulation of synaptic activity and mechanisms of adaptation, remodeling and plasticity in the nervous system
Neurobiology of Pain
Neurodegeneration and neuroprotection
Non-pharmacological neuro-rehabilitation of motor control in elderly and neurological patients
Neuronal and connective organization of the cerebral cloister of mammals
Role of cortical structures (prefrontal, premotor, motor, hippocampal), subcortical (striatum, amygdala, red nucleus, trunk brain centers) and cerebellar structures in the acquisition of associative learning tasks
Participation of mitochondria and second messengers in neurodegenerative processes
Involvement of the Endogenous Cannabinoid System in Neural Differentiation
Methods of phenotyping of mice and rats using electrophysiological recording (EEG) techniques
Learning and memory processes in "Drosophila melanogaster".
Neural processes that underlie learning and memory in the awake animal. Neural substrates of appetitive and exploratory behaviors
Oscillatory properties of the cerebral cortex
Psychoses, Personality Disorders, Child and Adolescent Mental Health
Recovery of visual function in partial retinal lesions and experimental models of amblyopia
Regeneration in the CNS: nuclear receptors
Functional relationships between sleep physiology and memory consolidation processes
Systematic reviews and meta-analyzes
Cellular and molecular pathways involved in neurodegenerative processes (Parkinson's, Huntington's, Alzheimer's, and ischemia).
Endocannabinoid system in the healthy and diseased brain
Slow-release techniques of neuroactive substances incorporated into nanoparticles of biodegradable plastics of application in the central nervous system.
Psychotic disorders: clinical epidemiology and neurocognition.
Specific Training Complements
In case the doctor does not have the complete previous training required in the program, his / her admission to the program may be conditioned to the surpassing of specific training complements, which may be subjects or modules of master and degree. The complements assigned to the same doctorate may not exceed 15 ECTS credits and may be made prior or simultaneous to the tuition in academic tuition in the program.
In case of simultaneous realization the students will have to register for these complements at the moment of formalizing the tuition of academic tutelage in the program, which must be surpassed in the maximum term of three consecutive quarters. Failure to do so will result in student disqualification from the program.
Introduction to neuroscience
Experimental techniques in neuroscience